Chloroquine and arrhythmia

Dear friends, Now as US FDA has issued an emergency use authorization to allow hydroxychloroquine and chloroquine used for certain hospitalized patients with COVID-19, it is useful to know some risk predictors in those using drug in view of its much debated pro-arrhythmic potential. American college of cardiology has recently published an article regarding same.Continue reading “Chloroquine and arrhythmia”

Triadin knockout syndrome

Triadin Knockout syndrome New cause of recessive genetic LQTS Presents before 5 years of age sudden cardiac arrest common Beta blockers no use ECG show symmetric inversion in anterior leads +/- Qt prolongation These may be the genotype negative cases of CPVT Triadin links calsequestrin, ryanodine receptor and junctophilin to L type calcium channel inContinue reading “Triadin knockout syndrome”