
Ajmaline is a Rauwolfia derivative CLASS 1 A drug.It is mostly used for diagnosis of arrhythmias
USES
- Delta wave disappearance in WPW syndrome indicating accessory PW ERP >250 msec
- Demonstrating ST changes ,IVCD in occult chagasic myopathy
- In cases of BBB and syncope-to demonstrate etiology of heart block
- To induce Rt precordial STE in BRUGADA syndrome with normal ecg. (mc)
Adverse reactions
- Mild anticholinergic
- Mild depression of LV systolic fn
- Worsen AV conduction in His purkinje disease
- Rarely TdP occur
- Increase Defibrillation threshold
Ref-BW 11 th ed pg 677