Triadin knockout syndrome

Posted byVijayPosted inUncategorizedTags:, , ,

Triadin Knockout syndrome

New cause of recessive genetic LQTS

  • Presents before 5 years of age
  • sudden cardiac arrest common
  • Beta blockers no use
  • ECG show symmetric inversion in anterior leads +/- Qt prolongation
  • These may be the genotype negative cases of CPVT
  • Triadin links calsequestrin, ryanodine receptor and junctophilin to L type calcium channel in myocardium

Leave a Reply

Fill in your details below or click an icon to log in:

Gravatar
WordPress.com Logo

You are commenting using your WordPress.com account. ( Log Out /  Change )

Google photo

You are commenting using your Google account. ( Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. ( Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. ( Log Out /  Change )

Cancel

Connecting to %s

<span>%d</span> bloggers like this: